Prior to making her debut in Little Witches, she worked in a coffee shop.
She appeared in various films and episodes of television shows such as ER and Buffy the Vampire Slayer before her breakthrough role as a goth student in Robert Rodriguez's The Faculty.
She is also known for her roles as Cora Lijek in the Academy Award–winning film Argo (2012), Audrey Hanson on NBC's Heroes (2006–07), Wendy Peyser on FX's American Horror Story: Asylum (2012–13), and Emma Borden on Lifetime's The Lizzie Borden Chronicles (2015).
Since 2016, she had played Marjorie on HBO political comedy Veep, for which she has been nominated for a Screen Actors Guild Award.
It's pretty much an open secret that Clea is into women and is also very private about her life…leave this poor woman and her girlfriend alone.” - Chelsea And the best one: “I was kissing my boyfriend the other day and I accidentally gave him a lesbian kiss instead of a normal kiss.
Her parents got separated when she was twelve years old.Throughout her career, she has played a number of gay characters, most recently a closeted school teacher in American Horror Story: Asylum.And it seems life imitates art somewhat for actress Clea Du Vall who indulged in a passionate kissing session with a female friend in a Los Angeles park on Sunday.Some of her film credits includes Interrupted, Girl, The Faculty and The Grudge.She is the daughter of Stephen "Steph" Du Vall and Rosemary Hatch.